Cryptococcus neoformans is a ubiquitous yeast like fungus that causes opportunistic infection in immunocompromised individuals. Objective of this case report is to study the histopathological findings in various organs in a case of disseminated Cryptococcal infection diagnosed on autopsy involving Kidney, Liver, Spleen, Lungs and Brain in human immunodeficiency virus (HIV) infected patient. Detailed postmortem gross and histopathological assessment of various organs was done to find out the cause of death. Patient was a known case of HIV infection and presented to the emergency with complaints of headache and chest pain. History of altered sensorium was also present. Histopathological examination along with the help of special stains, made the diagnosis of disseminated Cryptococcal infection.
Rani et al. (Tue,) studied this question.