To investigate the scope and selectivity of Negishi coupling reactions involving aryl iodides in deep eutectic solvents.
Utilized deep eutectic solvents for the coupling reaction.
Applied aryl iodides with various alkyl or arylzinc reagents.
Analyzed the reaction outcomes to determine selectivity and efficiency.
Demonstrated enhanced selectivity for specific products in deep eutectic solvents.
Reactions showed potential for broader application with different aryl iodides.
Highlighting the efficiency of zinc reagents in comparison to traditional methods.
Abstract
Negishi coupling is a valuable synthetic protocol for the formation of C-C bonds. However, the use of highly reactive alkyl-or arylzinc reagents in these reactions usually requires them to be...
KI fragen
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Cite This Study
Murillo-Herrera et al. (Thu,) studied this question.