An outstanding challenge in molecular biology is the production of a complete and accurate set of protein interactions for a given organism. Todor et al, introduce a clever strategy to efficiently screen all protein interactions in Mycoplasma genitalium using AlphaFold3 (Todor et al, 2026). K. Drew highlights a recent study by Todor and colleagues (in this issue of Molecular Systems Biology) that presents an innovative strategy to systematically map all protein interactions in M. genitalium using AlphaFold3.
Kevin Drew (Tue,) studied this question.