Do PCR-negative Enterobacterales with an increased meropenem minimum inhibitory concentration require further testing?

Background: Rapid, accurate detection of CPE is essential for effective infection control responses. We sought to determine if PCR alone is sufficient for carbapenemase gene detection in Enterobacterales with a Vitek-2 meropenem minimum inhibitory concentration (MIC) above the screening threshold (>0.25 mg/L). 1