The study investigates how perinatal and peripartum genes are expressed in mothers and their neonates during preeclampsia.
Analyzed transcriptomic landscapes in mother-neonate dyads
Examined expression of perinatal and peripartum genes
Investigated signaling pathways involved
Identified context-dependent gene expression patterns in preeclampsia
Observed minimal overlap in gene expression between mothers and neonates
Highlighted diverse signaling pathways influencing gene regulation
Abstract
Perinatal and peripartum genes in PE are expressed in a context-dependent manner via diverse signaling pathways, with little overlap between mothers and neonates.