Assessing Radiation Pneumonitis Through Functional Lung Imaging: A Single Photon Emission Computed Tomography (SPECT)-Based Approach in Lung Cancer

Key Points

• The study aims to investigate the relationship between SPECT-based imaging parameters and the risk of radiation pneumonitis in lung cancer.
• Utilized single photon emission computed tomography (SPECT) imaging to assess lung perfusion and ventilation.
• Derived dosimetric parameters from SPECT data to analyze their association with radiation pneumonitis risk.
• Performed a correlation analysis between imaging parameters and clinical outcomes in lung cancer patients.
• Identified significant associations between SPECT-dosimetric parameters and the occurrence of radiation pneumonitis.
• Findings suggest that incorporating SPECT can enhance risk stratification for lung cancer therapies.
• Potential for lung-sparing treatment strategies based on SPECT assessments.