A Case of Linear IgA Bullous Dermatosis Induced by Vancomycin

Key Points

• The aim is to report a case of linear IgA bullous dermatosis induced by vancomycin, highlighting the clinical features and diagnostic methods used.
• Clinical case report of an 86-year-old male post-abdominal aortic aneurysm treatment
• Treatment regimen included multiple antibiotics with vancomycin
• Utilized fluorescence antibody methods for diagnosis and detection of IgA
• Implemented steroid therapies including topical and pulse steroid treatments
• Bulla developed at genital and palmoplantar regions 16 days after initiating vancomycin treatment
• IgA linear deposition detected in the basement membrane and epidermis via fluorescence testing
• Antibodies against BP180 detected by immunoblot
• Symptoms showed resolution after discontinuation of vancomycin, distinguishing it from severe drug eruptions