Cytomegalovirus Lymphadenitis Mimicking Relapsed Lymphoma After CD19 Chimeric Antigen Receptor ( CAR ) T Cell Therapy

Key Points

• The study aims to clarify the confounding presentation of cytomegalovirus lymphadenitis as relapsed lymphoma following CAR T cell therapy.
• Analysis of clinical cases of lymphadenopathy post CAR T cell therapy
• Diagnostic imaging and lab tests
• Comparison of lymphadenitis and lymphoma characteristics
• Cytomegalovirus lymphadenitis was frequently misdiagnosed as relapsed lymphoma
• Immunocompromised states increase the risk of such misdiagnoses
• Favorable outcomes observed with appropriate diagnosis and treatment interventions

Abstract