Pre-pregnancy BMI, gestational weight gain trajectories, and new-onset hypertensive disorders in ART singleton pregnancies: a retrospective cohort study | Synapse
February 25, 2026Open Access
Pre-pregnancy BMI, gestational weight gain trajectories, and new-onset hypertensive disorders in ART singleton pregnancies: a retrospective cohort study
Key Points
This research examines how pre-pregnancy BMI and weight gain patterns relate to hypertension in pregnancies from assisted reproductive technology (ART).
Retrospective cohort design
Analysis of singleton pregnancies from ART
Assessment of pre-pregnancy BMI and gestational weight gain trajectories
Evaluation of new-onset hypertensive disorders
Optimal pre-pregnancy BMI linked to lower hypertensive disorder risk
Conservative weight gain thresholds associated with reduced hypertension
Distinct weight gain patterns may influence hypertensive risk further
Abstract
Maintaining optimal pre-pregnancy BMI and adhering to the proposed, more conservative GWG thresholds for ART pregnancies may reduce HDP risk. Distinct GWG trajectories may further modulate this risk.