Biodegradable Prussian blue/manganese dioxide core–shell nanoparticles with open cages for imaging-guided chemo-photothermal combined therapy of cancer cells

Key Points

• The research aims to develop biodegradable nanoparticles that enhance imaging and therapy for cancer treatment.
• Developed PBMn core–shell nanoplatform with an open cage design.
• Utilized Prussian blue for photothermal therapy.
• Employed manganese dioxide to enhance MRI capabilities.
• Tested combined chemo-photothermal therapy on cancer cells.
• Demonstrated effective imaging-guided therapy using the PBMn nanoparticles.
• Achieved significant cancer cell death with the combined treatment approach.