Association Between Blood Heavy Metal Exposure and Lower Urinary Tract Symptoms in Middle-Aged and Elderly Men: Insights From NHANES and Mendelian Randomization Study. | Synapse
February 25, 2026
Association Between Blood Heavy Metal Exposure and Lower Urinary Tract Symptoms in Middle-Aged and Elderly Men: Insights From NHANES and Mendelian Randomization Study.
Key Points
The aim is to investigate the relationship between blood levels of heavy metals and lower urinary tract symptoms in men.
Analyzed data from NHANES (National Health and Nutrition Examination Survey)
Assessed blood levels of lead and mercury
Applied mendelian randomization methods to establish causality.
Elevated blood lead levels correlated with higher risk of LUTS
Increased mercury levels possibly indicate a causal effect on LUTS
Abstract
Elevated blood levels of lead and mercury are associated with increased risk of LUTS in men, with mercury possibly exerting a causal influence.