This article examines the morphological and functional changes occurring in the hip joint, particularly in the femoral head, in patients following COVID-19 infection. Special attention is given to the development of aseptic necrosis as one of the serious complications associated with post-COVID syndrome. Clinical, radiological, and histological findings demonstrate that impaired blood circulation, vascular thrombosis, and endothelial dysfunction contribute significantly to the pathogenesis of bone tissue damage. MRI studies reveal characteristic changes in signal intensity depending on the stage and severity of necrosis, while morphological analysis confirms necrobiotic, dystrophic, and destructive alterations in bone trabeculae, osteoid structures, and vascular components. The progression of the disease leads to fragmentation of bone tissue and sequestrum formation. Early diagnosis and timely treatment of post-COVID musculoskeletal complications are essential to prevent disability and improve patient outcomes. The findings highlight the importance of understanding the pathogenesis, morphological features, and clinical implications of aseptic necrosis of the femoral head in post-COVID patients.
Nurmamat et al. (Mon,) studied this question.