What question did this study set out to answer?

To assess the risk of recurrent spontaneous preterm birth (sPTB) in women with a history of sPTB and midtrimester cervical length measurements.

February 25, 2026Archives of Gynecology and Obstetrics0 citationsOpen Access

Additional risk stratification in women with a history of spontaneous preterm birth and a midtrimester cervical length > 25 millimeters

ESEmilie V. J. van Limburg Stirum SBSofie Breuking CDCharlotte E. van Dijk

Key Points

To assess the risk of recurrent spontaneous preterm birth (sPTB) in women with a history of sPTB and midtrimester cervical length measurements.
Evaluated women with history of sPTB before 34 weeks of gestation
Measured cervical length before 24 weeks of gestation
Compared risk of recurrent sPTB based on cervical length thresholds
Women with cervical length > 25-30 mm had almost four times higher risk of recurrent sPTB
No association between decrease in cervical length and risk of sPTB was identified
Future studies needed to evaluate benefits of cerclage for this population

Abstract

Women with a history of sPTB before 34 weeks of GA and a cervical length of > 25-30 mm before the 24 weeks of gestation have an almost four times higher risk for a recurrent sPTB, compared to those with a longer cervical length. No association was found between decrease in cervical length and the risk of sPTB. Future studies should assess whether women with a history of sPTB and a cervical length of > 25-30 mm benefit from cerclage and cutoff values could be revised accordingly.

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