Cerebrovascular Hemodynamic Responses to Breath-holding in Migraine: A Longitudinal Functional Near-infrared Spectroscopy Study Comparing a Calcitonin Gene-related Peptide Monoclonal Antibody and Oral Preventive Treatment

Key Points

• This research aims to investigate cerebrovascular hemodynamic responses to breath-holding in migraine patients.
• Longitudinal study design
• Utilized functional near-infrared spectroscopy to measure hemodynamic responses
• Compared effects of calcitonin gene-related peptide monoclonal antibody and oral preventive treatment on responses
• Cerebrovascular responses to breath-holding were assessed in migraine patients
• Differences in responses were noted between treatments
• Indications that monoclonal antibody treatment may alter hemodynamic patterns in migraine