What question did this study set out to answer?

This research aims to examine the prevalence of disorders of gut-brain interaction (DGBIs) in pediatric patients with inflammatory bowel disease (IBD) in remission.

February 26, 2026

Prevalence of disorders of gut-brain-interaction in pediatric patients with in-remission inflammatory bowel disease: An Italian multicenter study.

Key Points

This research aims to examine the prevalence of disorders of gut-brain interaction (DGBIs) in pediatric patients with inflammatory bowel disease (IBD) in remission.
Conducted a multicenter observational study in pediatric patients with quiescent IBD and healthy controls.
Compared the prevalence of DGBIs between IBD patients and control group.
Analyzed psychological and nutritional factors as predictors of DGBIs.
Found a numerically higher prevalence of DGBIs in IBD patients compared to controls, though not statistically significant.
Identified significantly more upper gastrointestinal DGBIs in IBD patients.
Determined that 5-ASA medication may lower the likelihood of developing DGBIs.

Abstract

In our cohort, the overall DGBIs prevalence was numerically but not significantly higher in quiescent-IBD patients compared to controls, while upper gastrointestinal DGBIs were significantly more frequent in IBD patients. Psychological and nutritional factors emerged as strong predictors of DGBIs, while 5-ASA may be associated with lower likelihood of DGBIs.

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Cite This Study

Quatrale et al. (Mon,) studied this question.

synapsesocial.com/papers/699fe3af95ddcd3a253e7cbc https://doi.org/https://doi.org/10.1002/jpn3.70386

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