Background: Oral reactive lesions are frequent lesions with similar clinical features. The present study aimed to determine the frequency of oral reactive soft tissue lesions and their correlation between clinical and histopathological features. Methods: In this retrospective study archives of oral pathology were reviewed. Data collected through a checklist includes patient demographic variables (gender, age), lesion location, and clinical and histopathologic diagnosis. Data was analyzed in SPSS26 software with chi2, T, and kappa co-efficient tests. P values were considered at 0.05. Results: In the present study, the frequency of oral reactive lesions was 108(16.4%). The most frequent lesions were irritation fibroma and pyogenic granuloma with forty-two cases for each lesion. Gingivae and buccal mucosa were the most frequent sites respectively. Women had significantly more oral reactive lesions. The first clinical diagnosis was irritation fibroma. The correlation between clinical and histopathologic diagnosis based on the kappa coefficient was 0.623. The most and the lowest consistent clinical diagnoses with the histopathological diagnosis were epulis fissuratum and peripheral ossifying fibroma respectively. Conclusion: The most frequent lesions were irritation fibroma and pyogenic granuloma. Gingivae and buccal mucosa were the most frequent sites respectively. Women had significantly more reactive lesions—the correlation between clinical and histopathologic diagnosis was 0.623. The understanding of clinical features of soft tissue oral reactive lesions helps to achieve a clearer clinical diagnosis and may contribute to adequate treatment and positive prognosis.
Afshar et al. (Sun,) studied this question.