Physiological, Biochemical and Toxigenic Properties of Growing on Technogenic Substrates

The potential danger of toxin-forming fungus S. chartarum in the walls of buildings in St. Petersburg was assessed, its chemotype-specific signs, and toxicity of conidia and culture fluids were studied. We studied the composition of proteins, the relative quantitative content of trichothecene mycotoxins, as well as the qualitative composition of triprenylphenols of this fungus for the first time in Russia. It was noted that S. chartarum is often found in the St. Petersburg buildings materials containing cellulose, dominating in terms of abundance to other indoor fungi. It was shown that the toxic activity of S. chartarum conidia to Paramecium caudatum is determined by trichothecene mycotoxins, and the toxicity of culture liquids is determined by triprenyl phenols, in particular, stachybotridial. The potential ability detected to synthesize macrocyclic trichothecene mycotoxins in 27% of the S. chartarum strains and 53% to synthesize stachylysin indicates the danger of these micromycetes for the biodamaged premises occupants.