Bariatric surgery reduced OSA prevalence by 32.1 percentage points and new-onset OSA by 5.8 percentage points over 20 years versus usual care.
Does bariatric surgery improve remission and prevent new onset of obstructive sleep apnea in individuals with obesity compared to usual obesity care?
Bariatric surgery is associated with durable long-term improvements in obstructive sleep apnea, including higher remission and lower new-onset rates over 20 years compared to usual care.
Absolute Event Rate: 0% vs 0%
OBJECTIVE: Bariatric surgery has been suggested to improve obstructive sleep apnea (OSA) in short-term studies, but long-term evidence is limited. We evaluated remission and new onset of OSA over 20 years in participants from the Swedish Obese Subjects (SOS) study, comparing bariatric surgery with usual obesity care. METHODS: The SOS study is a nonrandomized, controlled intervention study including 4047 individuals who received bariatric surgery (n = 2010) or usual obesity care (n = 2037). OSA status was assessed via questionnaires at baseline and at 1, 2, 3, 4, 6, 8, 10, 15, and 20 years. We examined remission and new onset of OSA among participants with or without the condition at baseline, comparing surgery to usual care. RESULTS: On average over 20 years, bariatric surgery was associated with a 32.1 percentage points lower prevalence of OSA in participants with baseline OSA (95% CI: -36.9 to -27.2; p < 0.001) compared to usual care. Among those without baseline OSA, surgery patients had a 5.8 percentage points lower prevalence of new-onset OSA (95% CI: -7.1 to -4.6; p < 0.001). CONCLUSIONS: Bariatric surgery was associated with durable OSA benefits, including higher remission and lower long-term new onset of OSA compared to usual obesity care. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01479452.
Arnetorp et al. (Wed,) reported a other. Bariatric surgery reduced OSA prevalence by 32.1 percentage points and new-onset OSA by 5.8 percentage points over 20 years versus usual care.