Characterization and therapeutic potential of vBPaeMQR7: a highly efficient lytic bacteriophage against multidrug-resistant Pseudomonas aeruginosa

Key Points

• The aim is to characterize vB_PaeM_QR7 as a potential treatment for infections caused by multidrug-resistant Pseudomonas aeruginosa.
• Isolation of vB_PaeM_QR7 bacteriophage
• Testing its efficacy against 10 MDR P. aeruginosa isolates
• Characterization of resistance profiles of tested strains
• vB_PaeM_QR7 demonstrated lytic activity against 10 MDR P. aeruginosa isolates
• Effective against both cephalosporin- and carbapenem-resistant strains
• Supports the potential use of vB_PaeM_QR7 as an alternative antimicrobial therapy