Diagnostic Performance of New Commercial IGRAs for Mycobacterium tuberculosis Infection: An updated Systematic Review and Meta-analysis

Key Points

• This research aims to evaluate the diagnostic performance of new commercial IGRAs for Mycobacterium tuberculosis infection.
• Conducted a systematic review and meta-analysis of new IGRA tests.
• Reviewed accuracy and agreement with WHO-endorsed IGRAs.
• Assessed evidence quality based on bias and precision.
• Two out of eight new tests demonstrated promising accuracy.
• Tests showed high agreement with WHO-endorsed IGRAs.
• Overall evidence quality was rated as low due to potential biases.