Method of Synthesis of Quinoline Derivatives Based on Ethyl-3-(4-Methyl-2-Oxo-1,2-Dihydroquinoline-3-yl)Propanoates

Key Points

• The aim is to develop a method for synthesizing novel quinoline derivatives that could have potential pharmaceutical applications.
• Utilized a synthetic method involving ethyl 3-(4-methyl-2-oxo-1,2-dihydroquinolin-3-yl)propanoates.
• Reacted with α-phenylenediamine, α-aminophenol, and α-aminobenzenedithiol.
• Targeted the formation of heterocyclic hybrid systems.
• Successfully synthesized 3-(2-(1H-benzo[d]imidazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones.
• Synthesized 3-(2-(benzo[d]oxazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones.
• Produced 3-(2-(benzo[d]thiazol-2-yl)ethyl)-4-methylquinolin-2(1H)-ones.