Differential cell signaling testing for cell-cell communication inference from single-cell data by dominoSignal

Key Points

• The research aims to develop a method for inferring cell-cell communication pathways from single-cell data using dominoSignal.
• Developed a differential cell signaling method called dominoSignal for analysis.
• Applied the method to single-cell datasets to assess communication.
• Provided code and supplemental information for reproducibility.
• Enabled accurate inference of cell-cell communication in complex tissues.
• Showed enhanced understanding of signaling pathways at the single-cell level.