Urinary Metabolomic Characterization of Meclofenoxate Based on UHPLC-Q Exactive HF Orbitrap MS Technology

Key Points

• The research aims to characterize changes in human urine metabolites following the administration of meclofenoxate.
• Utilized ultra performance liquid chromatography coupled with Q Exactive HF Orbitrap mass spectrometry.
• Examined urine samples from individuals using meclofenoxate.
• Analyzed metabolite profiles to identify changes post-treatment.
• Identified significant alterations in specific urine metabolites after meclofenoxate use.
• Found potential biomarkers linked to meclofenoxate administration.
• Demonstrated the effectiveness of UHPLC-Q Exactive HF technology for metabolomic studies.