Our findings showed detection of EGFRvIII in 9.5% of gastric adenocarcinoma cases. Although the sample size presents a limitation, the increase in expression of this variant appears to be independent of the patients' gender and age. Notably, the association of this variant with the signet-ring cell adenocarcinoma subtype is a significant finding that warrants further investigation.
Zare‐Mirzaie et al. (Thu,) studied this question.