Axillary Recurrence After a Negative Sentinel Lymph Node Biopsy (SLNB) for Initial Positive Node Breast Cancer Postneoadjuvant Therapy: Insights From a Systematic Review and Meta-Analysis.

Key Points

• The aim is to evaluate the incidence of axillary recurrence after negative sentinel lymph node biopsy in initially positive node breast cancer patients treated with neoadjuvant therapy.
• Conducted a systematic review and meta-analysis of relevant studies.
• Selected studies focused on initially node-positive breast cancer patients.
• Analyzed recurrence rates following negative sentinel lymph node biopsy.
• Found a low incidence of axillary recurrence post negative sentinel lymph node biopsy.
• Support reliability of sentinel lymph node biopsy in staging axilla.
• Suggest that negative sentinel lymph node biopsy can inform treatment strategies effectively.

Abstract