Protective effects of Abelmoschus manihot flower extracts against blue light-emitting diode light-induced retinal photoreceptor cell damage in vivo and in vitro.

Key Points

• This research aims to investigate the protective effects of Abelmoschus manihot extracts against retinal damage caused by blue light and oxidative stress.
• In vivo experiments on retinal cells exposed to blue light.
• In vitro analysis of cellular effects of AME extracts.
• Assessment of oxidative stress markers and apoptosis rates.
• AME extracts significantly reduce retinal degeneration caused by blue light exposure.
• Activation of the nrf2 pathway was observed, indicating a protective mechanism.
• Reduction in apoptosis rates of photoreceptor cells was noted.