Influence of the Structure of Derivatives of Pyridazino4,5-Cquinoline and Quinoline Derivatives on Their Sorption on Octadecylisilica Gel

Key Points

• To analyze how the molecular structure of specific derivatives influences their retention in chromatography.
• Analyzed pyridazino[4,5-c]quinoline and quinoline derivatives.
• Utilized reversed-phase high-performance liquid chromatography (HPLC).
• Examined the influence of physicochemical parameters on retention values.
• Identified a relationship between molecular structure and retention under HPLC.
• Showed that physicochemical parameters significantly impact retention factor values.