Serum vitamin D and lean non-alcoholic fatty liver disease: a nonlinear 'L-shaped' association in a national cross-sectional study.

Key Points

• The study aims to explore the association between serum vitamin D levels and lean non-alcoholic fatty liver disease (NAFLD).
• National cross-sectional analysis conducted on a large population
• Focused on serum vitamin D concentrations
• Identified associations specifically in lean NAFLD cases
• Found a significant 'L-shaped' nonlinear association between serum vitamin D and lean NAFLD
• Strong association observed at serum vitamin D levels below approximately 60 nmol/L
• Revealed an epidemiological inflection point that suggests different effects at various vitamin D levels