Long-term and second recurrence following curative ESD for synchronous multiple early gastric neoplasia: a single-center cohort study

Key Points

• To evaluate long-term and second recurrence risks following curative endoscopic submucosal dissection (ESD) for synchronous multiple early gastric neoplasia (SM-EGN).
• Conducted a single-center cohort study.
• Analyzed recurrence rates after curative ESD.
• Implemented risk-adapted surveillance protocols for patients.
• Patients with SM-EGN showed a persistently higher risk of recurrence after ESD.
• No significant survival difference was noted in the second recurrence group.
• Intensive monitoring helped manage second recurrence effectively.