Nucleic acids, such as DNA and RNA, are essential biological macromolecules that store and transmit genetic information, acting as blueprints for protein synthesis and carrying hereditary traits across generation. Pesticides effects on nucleic acids function. Ethion 50% EC is a carbamate insecticide. In the present study decreased levels of DNA & RNA was observed in all the tissues of freshwater fish Labeo rohita exposed to 24 hrs lethal and sub lethal & 5days, 10 days sublethal concentrations of Ethion 50%EC. Inhibition of DNA synthesis, thus might affect both protein as well as amino acid levels by decreasing the level of RNA in protein synthesis machinery. Pesticides are potential inhibitor of DNA synthesis, which might result in reduction of RNA level.
*Dr. Prsanna Chimata (Sun,) studied this question.