Retrospective Comparison of Operational Metrics Across Diagnostic Approaches for Molecular Testing in Lung and Colon Cancers in a Community-Based Setting

Key Points

• The aim is to compare operational metrics of different diagnostic approaches for molecular testing in lung and colon cancers.
• Conducted a retrospective review of operational metrics for various diagnostic methods.
• Analyzed turnaround times, detection rates, and rates of quantitative not sufficient results.
• Evaluated performances of SGP, OFA, and SO-NGS in a community-based setting.
• SGP provided the fastest turnaround time but had lower detection and higher quantitative not sufficient rates in non-small cell lung cancer.
• OFA managed to balance turnaround time, QNS rates, and detection effectively.
• SO-NGS offered comprehensive detection but resulted in longer turnaround times and higher QNS rates.