What does this research mean for the field?

Intraovarian platelet-rich plasma (PRP) may activate dormant follicles in women with poor ovarian response during in vitro fertilization. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the role of intraovarian PRP in activating dormant follicles for women with poor ovarian response during IVF.

March 2, 2026Archives of Gynecology and Obstetrics0 citationsOpen Access

Unlocking ovarian rejuvenation with platelet-rich plasma: systematic review and proposed clinical framework for Controlled use in poor prognosis patients undergoing in vitro fertilisation

AAArwa A. Alageel

Key Points

To evaluate the role of intraovarian PRP in activating dormant follicles for women with poor ovarian response during IVF.
Conducted a systematic review of existing literature on the use of intraovarian PRP.
Focused on outcomes relevant to women with poor ovarian response.
Analyzed the quality and heterogeneity of current studies supporting PRP use.
Intraovarian PRP shows potential in activating dormant follicles.
Current evidence is limited and varies greatly in quality.
Use of PRP should be within structured clinical or research protocols until better studies are available.

Abstract

Intraovarian PRP may have a potential role in activating dormant follicles in a selected subset of women with poor ovarian response. However, the current evidence remains limited and heterogeneous, supporting its use only within structured clinical or research protocols until higher-quality, standardised studies are available.

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