Modern life science has long taken the neural network as the only core information regulation system of the human body, which can hardly explain the holistic homeostasis, diffuse signal transmission, meridian and zang-fu theory of Traditional Chinese Medicine (TCM), and the long-term holistic effects of lifestyle on physical and mental states. More than 60% of the human body is water, and the continuous fluid network composed of interstitial fluid and lymph is a long-neglected global regulation system. This paper puts forward the Human Dual-Network Synergy Theory: there are two inter-nested, functionally complementary and synergistic information regulation systems in the human body, namely the Wired Precision Neural Network based on neurons and the Diffuse Global Water Network based on body fluid. The Diffuse Global Water Network is highly consistent with the TCM meridian system and is its core material and information carrier. The two networks realize physical coupling and two-way signal conversion through nerve endings, forming a complete closed-loop regulation of local precision and global holistic coordination. As the largest endogenous signal generator in the human body, gut microbiota participates in dual-network regulation through neural and fluid pathways. The large intestine, lung and spleen-stomach form a signal transmission-reception-integration pathway, providing a modern scientific explanation for the TCM theory that "the lung and the large intestine are internally-externally related". This theory can systematically explain core physical and mental phenomena such as meditation, diet and sub-health, and puts forward a number of testable predictions, providing a new theoretical support for the modernization of TCM and psychosomatic medicine.
Jian Wen (Sat,) studied this question.