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In vivo engineering of CAR-T cells: delivery strategies and clinical translation | Synapse
March 3, 2026
Open Access
In vivo engineering of CAR-T cells: delivery strategies and clinical translation
YG
Yang Gao
Tongji Hospital
JH
Jianlin Hu
Tongji Hospital
NA
Ning An
Hubei Provincial Center for Disease Control and Prevention
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Key Points
CAR-T cells demonstrate potential to effectively target and combat cancer cells, enhancing treatment options.
Delivery strategies, including various methods, significantly impact the performance and functionality of CAR-T cells in vivo.
Clinical translation efforts focus on adapting these advanced CAR-T cell therapies for real-world cancer treatment environments.
Optimizing delivery methods may enable broader accessibility and effectiveness of CAR-T therapies, impacting patient care.
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Gao et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75a56c6e9836116a20082
https://doi.org/https://doi.org/10.1186/s40364-026-00899-y
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