A chlorine-free reaction was developed to synthesize triazaaryl phosphine sulfides and their analogues from white phosphorus (P4). Mediated by diphenyl disulfide/diselenide and sodium hydride, the P-N bond was formed directly from P4 with N-heteroaromatic substrates. This method features a one-pot process, mild conditions, and good substrate tolerance. A series of triazaaryl phosphine sulfides and their analogues were prepared with mild to excellent yields (58%-98%). In addition, the disulfide/diselenide media could be recycled.
Chen et al. (Tue,) studied this question.