Tumor-Associated Neutrophils and Desmoplastic Reaction in Breast Cancer Microenvironment: Association with Tumor Grade and Clinicopathological Features

Key Points

• High levels of tumor-associated neutrophils are primarily associated with aggressive tumor grades.
• Myxoid stroma may serve as a significant indicator of a highly aggressive tumor microenvironment.
• The findings suggest a need for further validation in larger, prospective studies for robust conclusions.
• This preliminary association highlights the importance of understanding clinicopathological features in breast cancer.

Abstract