Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats | Synapse
March 3, 2026Open Access
Identification of key genes associated with muscle atrophy after spinal cord injury and experimental verification in rats
Key Points
Muscle atrophy may be influenced by genes FOS and CCL2, indicating potential treatment targets.
FOS and CCL2 likely play a role in the molecular pathophysiology of muscle atrophy after spinal cord injury.
Analysis focused on gene expression and mechanisms involved in spinal cord injury-related muscle loss in rats.
Identifying these genes may enable better treatment strategies for muscle atrophy post-injury.
Abstract
FOS and CCL2 may be involved in the molecular pathophysiology of muscle atrophy after SCI, serving as potential targets for diagnosis or treatment of SCI-related muscle atrophy.