Stereospecific method for separation and quantification of Ezetimibe and its stereoisomers using ultra-performance convergence chromatography (UPC2)

Key Points

• The method effectively separates ezetimibe and its stereoisomers, allowing for accurate quantification in formulations.
• An impressive resolution of 10.5 between stereoisomers showcases the method's high efficiency and performance.
• Analysis employed ultra-performance convergence chromatography, providing rapid results while maintaining high analytical quality.
• This approach supports the improvement of drug formulation by allowing clear identification of ezetimibe stereoisomers, critical for dosage accuracy.