Gallic and ascorbic acids either alone or combined contribute to ameliorating lead-induced cerebral neurotoxicity in rats: A histological and immunohistochemical study

Key Points

• Lead-induced neurotoxicity is mitigated by gallic and ascorbic acids, showing an overall positive impact.
• Histological analysis demonstrated significant improvements in cerebral architecture with these treatments.
• The combination of gallic and ascorbic acids was particularly effective in reducing neurotoxic effects, enhancing recovery.
• These findings highlight the potential of these compounds in neuroprotection against environmental toxins.