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Discovery of a multi-epitope tuberculosis vaccine targeting phospholipase C virulence factors: an insilico approach | Synapse
March 3, 2026
Discovery of a multi-epitope tuberculosis vaccine targeting phospholipase C virulence factors: an insilico approach
BM
Bhavin Maru
AS
Ashish Shah
Key Points
The vaccine targeting phospholipase C aims to enhance the immune response against tuberculosis.
In silico experiments reveal multi-epitope constructs that elicit strong immune responses.
Assessment using computational modeling techniques efficiently identifies promising vaccine candidates.
This approach may facilitate the development of effective tuberculosis vaccines, needing further experimental validation.
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Maru et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75af9c6e9836116a217c2
https://doi.org/https://doi.org/10.1007/s10529-026-03690-z