Physical exercise mitigates motor and muscular deficits in the 3xTg-AD model of Alzheimer’s disease

Key Points

• Motor function improves significantly with physical exercise, indicating beneficial effects in 3xTg-AD.
• The analysis highlights the relationship between physical activity and reduced brain pathology in the Alzheimer’s model.
• Assessment of muscle and brain health indicates exercise mitigates adverse effects of Alzheimer’s disease.
• These findings suggest exercise should be considered as a complementary therapeutic strategy for managing Alzheimer’s.