Ficus carica leaf extract ameliorates cardiac injury through Nrf2/Keap1 pathway activation and dual oxidase inhibition.
Key Points
Cardiac injury mitigation occurs through dual oxidase inhibition, reducing oxidative stress and apoptosis.
FCLE treatment shows significant modulation of the Nrf2/Keap1 pathway, promoting cellular protection from damage.
Analysis utilizes biochemical assessments to evaluate the impact of FCLE on apoptotic signaling cascades in cardiac tissues.
This suggests potential therapeutic applications, though further clinical validation is needed.
Abstract
Our results suggest that FCLE mitigates cardiac injury by modulating oxidative stress and apoptosis through dual oxidases, the Nrf2/Keap1 pathway, and related apoptotic signaling cascades.