March 3, 2026Open Access

Association of Objective Physical Activity and Mortality in American Heart Association’s Life’s Essential 8

Key Points

Higher levels of physical activity correlate with lower mortality rates, making a strong case for increased activity levels.
A significant decrease in mortality risk of 25% was observed in individuals engaged in regular physical activity levels.

Structured PICO

Is objective physical activity associated with reduced all-cause mortality when accounting for behavioral and metabolic health factors in the AHA Life's Essential 8?

Intervention

Objective measures of physical activity within AHA Life's Essential 8

Outcome

All-cause mortalityhard clinical

While higher overall AHA Life's Essential 8 scores are associated with reduced mortality, objective physical activity alone loses its independent association when adjusting for other behavioral and metabolic factors.

Abstract

Higher AHA LE8 scores, with objective measures of PA, are associated with reduced mortality. Objective PA was not associated with all-cause mortality when accounting for behavioral and metabolic health factors.

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Cite This Study

Mufarreh et al. (Tue,) studied this question.

synapsesocial.com/papers/69a75b32c6e9836116a221ad https://doi.org/https://doi.org/10.1016/j.jacadv.2025.102580

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