March 3, 2026

Non-Anticoagulated Fresh Whole Blood Syringe Transfusion as an Alternative for Military Hemorrhage Resuscitation in Austere Environments

Key Points

Non-anticoagulated fresh whole blood transfusion shows promise for rapid hemorrhage resuscitation, with effective rates under 100 mL/min.
Testing indicates no significant clot burden and no hemolysis observed, highlighting safety at infusion rates up to 100 mL/min.
Assessment of conditions for military use shows potential in short donor-to-recipient times contributing to efficiency in care.
Further investigation on longer storage times and faster infusion rates may improve clinical safety and efficacy.

Abstract

These findings suggest that non-anticoagulated fresh whole blood may be transfused within 5 minutes at infusion rates of 100 mL/minute or less with no significant clot burden and no evidence of hemolysis. Longer storage times and faster infusion rates may also be clinical safe but require further investigation. This study indicates that there may be some potential use of this method in military units executing a fresh whole blood draw with short donor-to-recipient times.

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Discussion

Authors

Christopher J Scheiber

Sarah Glier

Justin Magin

Journals

Military Medicine

Actions

Institutions

University of North Carolina at Chapel Hill

Johns Hopkins Hospital

University of North Carolina Hospitals

References and Citations

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Non-Anticoagulated Fresh Whole Blood Syringe Transfusion as an Alternative for Military Hemorrhage Resuscitation in Austere Environments

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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