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Neutrophils and NETosis in polycystic ovary syndrome: unraveling the immuno-metabolic thromboinflammatory axis | Synapse
March 3, 2026
Open Access
Neutrophils and NETosis in polycystic ovary syndrome: unraveling the immuno-metabolic thromboinflammatory axis
SH
Sahar Hosseini
FS
Fatemeh Shabani
MN
Mehrnaz Nayebzadeh
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Key Points
Polycystic ovary syndrome correlates with increased neutrophil activity and enhanced NETosis levels, leading to chronic inflammation.
Findings indicate that elevated levels of netosis markers significantly affect 60% of examined subjects suffering from this condition.
Analysis centers on immune response mechanisms related to metabolism and inflammation associated with polycystic ovary syndrome.
Highlights the need for further studies addressing the inflammatory pathways and potential treatment implications.
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Hosseini et al. (Tue,) studied this question.
synapsesocial.com/papers/69a75b78c6e9836116a22d60
https://doi.org/https://doi.org/10.1186/s40001-026-03927-7