In-silico Identification of Novel Inhibitors Targeting Dengue Virus Serotype 3 RNA-Dependent RNA Polymerase

Key Points

• Inhibitors represent promising candidates for DENV-3, with computer modeling revealing effective interactions with the RNA-dependent RNA polymerase.
• Analysis utilized computational techniques to identify inhibitors, marking a crucial step toward developing effective antiviral treatments.
• Exhaustive computational studies contributed to uncovering these novel inhibitors, indicating potential pathways for further research.
• Findings may enable advancements in antiviral drug development, especially for respiratory viral infections like DENV-3 infections.

Abstract