Targeting Oxidative Stress and Apoptosis via PI3K/Akt/Nrf2 Pathway: The Therapeutic Role of Bletilla striata Polysaccharide in Diabetic Wound Repair

Key Points

• Bletilla striata polysaccharide significantly promotes healing in diabetic wounds, demonstrating its therapeutic potential.
• The study highlights a pivotal role of the PI3K/Akt/Nrf2 pathway in enhancing wound repair mechanisms in diabetic conditions.
• Analysis integrated oxidative stress management and anti-apoptotic effects to establish treatment protocols.
• This study suggests that natural polysaccharides like Bletilla striata may provide valuable therapeutic options in managing diabetes-related complications.

Abstract