Perinatal microbial exposure and the shaping of the early immune system: lessons from experimental models

Key Points

• Early microbial exposure influences immune pathways, impacting the development of the immune system.
• Experiments provide insights on how perinatal factors shape immune responses, potentially affecting lifelong health.
• Assessment using experimental models shows distinct changes in inflammation related to microbial exposure in infancy.
• Highlights the necessity for understanding microbial influence on immune development for improving health strategies.