Clinical phenotyping and inflammatory biomarkers of asthma–COPD overlap: a cross-sectional, single-center study in China

Key Points

• Findings reveal a distinct intermediate phenotype in asthma-COPD overlap, enhancing diagnostic clarity.
• The integration of clinical features and imaging metrics leads to a high diagnostic accuracy of 87% for ACO.
• Cross-sectional analysis evaluated various clinical phenotypes and inflammatory biomarkers in a single-center study.
• These insights suggest that a tailored anti-inflammatory treatment approach may significantly benefit patients with ACO.