March 3, 2026Open Access

Variations in bronchopulmonary dysplasia prevalence and outcomes by definition: a multicentre cohort study from the Chinese Neonatal Network

Key Points

Bronchopulmonary dysplasia prevalence was found to be high among very preterm infants in China, varying by definition used.
The Shennan 1988, NICHD 2018, and NRN 2019 definitions demonstrated improved predictive accuracy at discharge compared to NICHD 2001.
Multicentre cohort analysis revealed significant implications for clinical definitions of bronchopulmonary dysplasia outcomes.
Updating definitions in clinical use may enhance understanding and treatment of very preterm infants at risk of BPD.

Abstract

This study found a high prevalence of BPD among very preterm infants in China, varying by definitions. The Shennan 1988, NICHD 2018 and NRN 2019 definitions showed good agreement and better predictive accuracy for outcomes at discharge compared with NICHD 2001. These definitions could be prioritised for clinical use in our population.

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Discussion

Authors

Ge Yang

Ling Wang

Caixia Gao

Journals

BMJ Open

Actions

Institutions

Children's Hospital of Philadelphia

Mount Sinai Hospital

Guangzhou Medical University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Variations in bronchopulmonary dysplasia prevalence and outcomes by definition: a multicentre cohort study from the Chinese Neonatal Network

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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